Do not administer intravascularly. Appropriate medical treatment & supervision should always be readily available in case of rare anaphylactic reactions following vaccination. If any of the following occurs in temporal relation to receipt of pertussis-containing vaccine, the decision to give doses of pertussis-containing vaccine should be carefully considered: Temp ≥40°C w/in 48 hr of vaccination, not due to another identifiable cause; collapse or shock-like state w/in 48 hr of vaccination; persistent, inconsolable crying lasting ≥3 hr w/in 48 hr of vaccination; convulsions w/ or w/o fever, occurring w/in 3 days of vaccination. Childn w/ new onset or progressive severe neurological disorders; individuals w/ thrombocytopenia or a bleeding disorder; immunosuppressed patients. Protective immune response may not be elicited in all vaccinees. Lactation. Safety & efficacy in childn <3 yr have not been established.
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